K+-independent Li+/Ca2+ exchanger transport K+-dependent Na+/Ca2+ exchanger transport PathwayStep4866 PathwayStep4865 PathwayStep544 Na+/Ca2+ exchanger transport Sodium/Calcium exchangers Authored: Jassal, B, 2009-06-05 Calcium ions are used by cells as ubiquitous signalling molecules that control diverse physiological events. Three mammalian gene families control Ca2+ transport across plasma membranes and intracellular compartments (Lytton J, 2007). They are the Na+/Ca2+ exchanger family designated NCX (SLC8) (three members NCX1-3) (Quednau BD et al, 2004), the Na+/Ca2+-K+ exchanger family designated NCKX (SLC24) (five members NCKX1-5) (Schnetkamp PP, 2004) and a Ca2+/cation exchanger (NCKX6, NCLX) whose physiological function remains unclear. Edited: Jassal, B, 2009-06-05 Pubmed12734757 Pubmed14770312 Pubmed17716241 Reactome Database ID Release 43425561 Reactome, http://www.reactome.org ReactomeREACT_19320 Reviewed: He, L, 2009-08-24