PathwayStep1224 PathwayStep1203 ABCG5:ABCG8-mediated export of cholesterol and phytosterols ABCG1-mediated transport of intracellular cholesterol to the cell surface ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes ABCG4 may mediate cholesterol efflux PEX-19 docks ABCD1/D2/D3 to peroximal membrane ABCA7:Apo1A-mediated phospholipid efflux ABCAs mediate lipid efflux ABCAs mediate lipid influx PathwayStep4852 PathwayStep4851 PathwayStep4850 PathwayStep4847 PathwayStep4848 PathwayStep4849 ABCA transporters in lipid homeostasis A defined subset of the ABC transporter superfamily, the ABCA transporters, are highly expressed in monocytes and macrophages and are regulated by cholesterol flux which may indicate their role in in chronic inflammatory diseases (Schmitz and Kaminski 2001, Schmitz et al. 2000). Authored: Jassal, B, 2011-07-04 Edited: Jassal, B, 2011-07-04 Pubmed11048892 Pubmed11229879 Reactome Database ID Release 431369062 Reactome, http://www.reactome.org ReactomeREACT_111158 Reviewed: D'Eustachio, P, 2011-08-23