PathwayStep4500 PathwayStep4499 Formation of the MCC complex Binding of the MCC complex to the APC/C complex Inactivation of APC/C via direct inhibition of the APC/C complex Authored: Yen, T, 2004-05-05 00:00:00 In the direct inhibition model, the cytosolic Mitotic Checkpoint Complex, consisting of hBUBR1, hBUB3, Cdc20 and Mad2, directly inhibits APC/C by binding to it. Pubmed11535616 Pubmed14593737 Pubmed9637688 Reactome Database ID Release 43141430 Reactome, http://www.reactome.org ReactomeREACT_1072 Reviewed: Peters, JM, 2006-03-27 22:55:09