oligopeptide fragment (8-16aa) oligopeptide fragment Translocation of antigenic peptides back to phagosomes via TAP After processing by the proteasome, some of the oligopeptides could be reinternalized to the phagosome lumen of the same phagosome through the TAP complex probably acquired during ER-phagosome fusion. Guermonprez et al. (2003) tested this model and observed abundant TAP complex in early phagosomes and its reduction over time. Electron microscopy analysis of purified phagosomes also showed the insertion of TAP2 into the phagosomal membrane. Authored: Garapati, P V, 2011-03-28 Edited: Garapati, P V, 2011-03-28 Pubmed14508489 Reactome Database ID Release 431236949 Reactome, http://www.reactome.org ReactomeREACT_111185 Reviewed: Desjardins, M, English, L, 2011-05-13 has a Stoichiometric coefficient of 2