MHC class I HC:Calnexin/BiP:Erp57 monoglucosylated MHC class I HC:Calnexin/BiP Interaction of Erp57 with MHC class I HC Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 Endoplasmic reticulum resident protein 57 (ERp57), is a member of the protein disulphide isomerase (PDI) family of thiol oxidoreducatases. It associates with Calnexin (CNX), and its soluble homolog calreticulin (CRT) and is recruited to MHC Class I Heavy Chain (HC). ERp57 is involved in the formation of HC disulphide bonds. Reactome Database ID Release 43983148 Reactome, http://www.reactome.org ReactomeREACT_75930 Reviewed: Elliott, T, 2011-02-10