1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus Authored: Williams, MG, 2011-10-28 Edited: Williams, MG, 2011-10-28 In the nucleus, inositol hexakisphosphate kinase 1 (IP6K1) and 2 (IP6K2) phosphorylate 1-diphospho-2,3,4,5,6-pentakisphosphate (1-PP-IP5) to make inositol 1,5-bisdiphospho-2,3,4,6-tetrakisphosphate (1,5-(PP)2-IP4) (Saiardi et al. 2001, Mulugu et al. 2007). Pubmed11502751 Pubmed17412958 Reactome Database ID Release 431855157 Reactome, http://www.reactome.org ReactomeREACT_150168 Reviewed: Challiss, John, 2012-11-09 Reviewed: Wundenberg, Torsten, 2012-11-06