D2,4,4(S)3-PGs D2,4(S)2-PG GalNAc is sulfated on position 4 once dermatan sulfate is formed Authored: Jassal, B, 2011-11-25 Edited: Jassal, B, 2011-11-25 Important functional domains in dermatan sulfate (DS) are generated by the action of an epimerase (which converts D-glucuronic acid into its epimer L-iduronic acid) together with 4-O-sulfation. These domains are named 4-O-sulfated iduronic acid blocks (Pachebo et al. 2009). Pubmed19661164 Reactome Database ID Release 432022063 Reactome, http://www.reactome.org ReactomeREACT_120903 Reviewed: D'Eustachio, P, 2012-03-28