Iduronate 2-sulfatase (IDS) hydrolyses sulfates from L-iduronate 2-sulfate units of dermatan sulfate Authored: Jassal, B, 2011-10-21 EC Number: 3.1.6.13 Edited: Jassal, B, 2011-10-21 Iduronate 2-sulfatase (IDS) hydrolyses 2-sulfate groups from L-iduronate 2-sulfate units of dermatan sulfate in the lysosome. Defects in IDS are the cause of mucopolysaccharidosis type II (MPSII, MIM:309900), also called Hunter syndrome (Wilson et al. 1990). Pubmed2122463 Reactome Database ID Release 431793182 Reactome, http://www.reactome.org ReactomeREACT_120781 Reviewed: D'Eustachio, P, 2012-03-28