(HA)50 (HA)50 20kDa HA fragments are translocated to lysosomes Authored: Jassal, B, 2012-03-05 Edited: Jassal, B, 2012-03-05 Pubmed11827788 Pubmed22216413 Reactome Database ID Release 432160906 Reactome, http://www.reactome.org ReactomeREACT_121181 Reviewed: D'Eustachio, P, 2012-03-28 The smallest fragments HYAL2 can generate are 20kDa (approximately 50 disaccharide unit) HA fragments. These fragments are internalized and delivered to lysosomes (Knudson et al. 2002, Erickson & Stern 2012) where another hyalurindase, HYAL1, can degrade them further.