HS/HPIN-PGs HS/HPIN-PGs HS-GAGs translocate to the lysosome for degradation As part of the natural turnover of GAGs, extracellular KSPGs translocate to the lysosome to be degraded. The translocation process is unsure but could be either endocytosis from outside the cell and/or autophagy from inside the cell (Winchester 2005). Authored: Jassal, B, 2011-12-14 Edited: Jassal, B, 2011-12-14 Pubmed15647514 Reactome Database ID Release 432024084 Reactome, http://www.reactome.org ReactomeREACT_121392 Reviewed: D'Eustachio, P, 2012-03-28