SLC6A19-mediated uptake of neutral amino acids Authored: D'Eustachio, P, 2008-06-02 20:10:30 Edited: D'Eustachio, P, 2008-09-12 21:44:24 Pubmed15286787 Pubmed15286788 Reactome Database ID Release 43375473 Reactome, http://www.reactome.org ReactomeREACT_14843 Reviewed: Jassal, B, 2008-06-03 13:06:01 SLC6A19, associated with the plasma membrane, mediates the uptake of neutral amino acids. Uptake of an amino acid molecule is accompanied by uptake of a sodium ion. The protein is abundant in cells in the small intestine and kidney. Its deficiency is associated with Hartnup disorder, the failure to take up neutral amino acids efficiently from the gut lumen and to reabsorb them in the proximal kidney tubule (Kleta et al. 2004; Seow et al, 2004). ligands of SLC6A19 ligands of SLC6A19