SLC7A5-mediated uptake of neutral amino acids Authored: D'Eustachio, P, 2008-06-02 20:10:30 Edited: D'Eustachio, P, 2008-06-02 20:10:30 Pubmed10049700 Pubmed10391915 Reactome Database ID Release 43352232 Reactome, http://www.reactome.org ReactomeREACT_13642 Reviewed: Jassal, B, 2008-06-03 13:06:01 SLC7A5, complexed with SLC3A2 in the plasma membrane, mediates the uptake of neutral amino acids. The process is Na+-independent and not coupled to H+ transport. As measured by Northern blotting SLC7A5 is widely expressed in the body. In situ hybridization studies indicate that the gene product is widely expressed in the body but not in the kidney (Pineda et al. 1999; Prasad et al. 1999). ligands of SLC7A5 ligands of SLC7A5