sucrose + H2O => glucose + fructose Authored: D'Eustachio, P, 2006-11-03 14:36:07 Digestion of sucrose to yield glucose and fructose EC Number: 3.2.1.26 EC Number: 3.2.1.48 Extracellular sucrose is hydrolyzed to yield glucose and fructose in a reaction catalyzed by the sucrase domain of sucrase-isomaltase (Conklin et al. 1975). In the body, this enzyme is found on the external face of enterocytes in microvilli of the small intestine (Hauri et al. 1985). The sucrase-isomaltase polypeptide is cleaved into its sucrase and isomaltase domains, which remain associated and, by analogy to the corresponding pig enzyme, are thought to dimerize (Cowell et al. 1986). Pubmed3800897 Pubmed3897250 Pubmed807575 Reactome Database ID Release 43189069 Reactome, http://www.reactome.org ReactomeREACT_9409 Reviewed: Nichols, BL, 2007-01-15 21:51:24