Conversion of palmitic acid to palmitoyl-CoA Authored: Gopinathrao, G, 2007-07-29 21:03:03 EC Number: 6.2.1.3 Membrane-associated acyl-CoA synthetase long-chain family member 1 (ACSL1) catalyzes the reaction of palmitate, CoASH, and ATP to form palmitoyl-CoA, AMP, pyrophosphate, and water. Human ACSL1 has not been characterized in detail, but available data suggest that it is associated specifically with the membrane of the endoplasmic reticulum and that it can act on oleic acid as well as on palmitic acid (Malhotra et al. 1999). Pubmed10548543 Reactome Database ID Release 43201035 Reactome, http://www.reactome.org ReactomeREACT_11137 Reviewed: D'Eustachio, P, 2007-07-31 18:50:15 palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL1]