capped, methylated pre-mRNA:CBC Complex capped, methylated pre-mRNP:CBC complex Formation of pre-mRNPs After the nascent pre-mRNA undergoes the initial capping and methylation reactions, it gets associated with numerous factors, including the various heterogeneous nuclear ribonucleoproteins (hnRNPS), the nuclear Cap-Binding Complex, and many splicing factors that make the pre-mRNA a substrate for splicing, 3'-end processing, and in some cases editing. Reactome Database ID Release 4372103 Reactome, http://www.reactome.org ReactomeREACT_1877