capped, methylated pre-mRNA:CBC Complex capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex Internal Methylation of mRNA Edited: Joshi-Tope, G, 0000-00-00 00:00:00 In addition to the methylation of the 5'-cap, there is methylation of internal nucleotides in the mRNA. This methylation can occur in translated and untranslated regions. One to three methyl groups have been seen per mRNA molecule, but methylation is non-stoichiometric. The most frequent methylation observed is at the N6 position of adenosine. The function of mRNA internal methylation, if any, is unknown. Pubmed9409616 Reactome Database ID Release 4372095 Reactome, http://www.reactome.org ReactomeREACT_1720