JAM-A Homodimer JAM-A homodimerises Authored: Ouwehand, W.H., 2007-11-12 16:45:54 JAM-A is the most widely expressed member of the family, and has been shown to be expressed on endothelial and epithelial cells, on platelets, and on a number of leukocyte subsets. In endothelial cells, JAM-A locates to the tight junctions, where it appears to engage in homophilic binding to JAM-A on adjacent cells, an interaction that is considered to play a critical role in angiogenesis. Pubmed16783819 Pubmed17505016 Pubmed17525755 Pubmed17615384 Reactome Database ID Release 43202726 Reactome, http://www.reactome.org ReactomeREACT_11999 Reviewed: Zwaginga, JJ, 2007-11-12 16:47:00 has a Stoichiometric coefficient of 2