P-selectin bound to its ligand Selectin P-selectin binds P-selectin ligand Authored: Ouwehand, W.H., 2007-11-12 16:45:54 PSGL-1 is expressed as a homodimer of two 120-kDa subunits that binds all three selectins, with the highest affinity for P-selectin, and is known to be constitutively expressed on the surface of platelets and most types of leukocytes. Besides playing a critical role in the inflammatory response by mediating leukocyte-leukocyte and leukocyte-endothelium interactions, PSGL-1 also participates in the hemostatic process by mediating leukocyte-platelet interactions. Pubmed14615387 Pubmed17322099 Reactome Database ID Release 43202724 Reactome, http://www.reactome.org ReactomeREACT_12081 Reviewed: Zwaginga, JJ, 2007-11-12 16:47:00 has a Stoichiometric coefficient of 2