pTie2 and SHP2 complex pTie2:Ang-1 Interaction of Tie2 and Shp2 Authored: Garapati, P V, de Bono, B, 2008-03-05 10:26:56 Edited: Garapati, P V, 2009-03-16 17:55:42 Pubmed10521483 Pubmed9764820 Reactome Database ID Release 43204873 Reactome, http://www.reactome.org ReactomeREACT_16906 Reviewed: Trowsdale, J, 2009-02-13 11:51:02 Shp2 interact with Tyr816 in the juxtamembrane region and Tyr1108 and Tyr1113, respectively, in the C-terminal tail region of Tie2/Tek.