IRF2:promoters of INF alpha, INF beta Promotor region of interferon alpha Promotor region of interferon beta IRF2 binds the promoters of Interferon alpha and beta Authored: Akkerman, JW, 2010-10-29 Edited: Jupe, S, 2010-11-12 Interferon regulatory factor 2 (IRF-2) represses the action of IRF-1 on type I interferon genes (Harada et al, 1989, 1990; Palombella & Maniatis, 1992) by competing with IRF-1 for binding at the PRDI site. Pubmed1630448 Pubmed2475256 Reactome Database ID Release 43994038 Reactome, http://www.reactome.org ReactomeREACT_25232 Reviewed: Ouwehand, WH, 2010-11-12 has a Stoichiometric coefficient of 2