Basigin bound to CyPA Basigin binds CyPA Authored: de Bono, B, Garapati, P V, 2008-02-26 12:30:30 Cyclophilin A (CyPA)1 is an intracellular protein belonging to the immunophilin family and is recognized as the major target for the potent immunosuppressive drug cyclosporin A. CD147 is the natural cell surface receptor for CyPA. It is demonstrated that CD147 is an essential component in the CyPA-initiated signaling cascade that culminates in ERK activation. Pubmed11943775 Reactome Database ID Release 43204485 Reactome, http://www.reactome.org ReactomeREACT_12497 Reviewed: Trowsdale, J, 2008-02-26 12:02:59