G Protein Trimer Complex (olfactory) G Protein trimer formation (olfactory) Authored: Caudy, M, 2009-03-02 00:28:58 Edited: Caudy, M, 2009-04-28 19:52:59 Pubmed14983052 Pubmed17509148 Pubmed17873857 Pubmed17973576 Pubmed18043707 Pubmed1840504 Pubmed9459443 Reactome Database ID Release 43381749 Reactome, http://www.reactome.org ReactomeREACT_15416 Reviewed: Vosshall, L, 2008-12-02 23:19:16 The heterotrimeric guanine nucleotide-binding proteins (G-proteins) function to transduce signals from this vast panoply of receptors to effector systems including ion channels and enzymes that alter the rate of production, release or degradation of intracellular second messengers. GPCRs activate the G-proteins, which consist of an alpha-subunit that binds and hydrolyses guanosine triphosphate (GTP), a beta and a gamma subunit.