FP receptor can bind PGF2-alpha Authored: Jassal, B, 2009-04-02 10:56:26 Edited: Jassal, B, 2009-04-02 10:56:26 Prostaglandin F receptor (FP) is a GPCR for Prostaglandin F2alpha and is encoded by the PTGFR gene (Abramovitz M et al, 1994). Main effects of prostaglandin binding to the receptor are uterine contraction and bronchoconstriction. These effects are mediated by coupling with the G protein alpha q/11 subunit which activates a phosphatidylinositol-calcium second messenger system (Carrasco MP et al, 1997). Pubmed8300593 Pubmed9462300 Reactome Database ID Release 43416929 Reactome, http://www.reactome.org ReactomeREACT_18276 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22 FP receptor:PGF2-alpha