ATP:UTP P2RY2:ATP P2Y2 receptor binds ATP and UTP Authored: Jassal, B, 2009-04-14 09:13:21 Edited: Jassal, B, 2009-04-14 09:13:21 Pubmed12458155 Pubmed8159738 Pubmed9364473 Reactome Database ID Release 43417927 Reactome, http://www.reactome.org ReactomeREACT_18310 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22 The P2Y2 receptor (Parr CE et al, 1994) is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. The effects of P2Y2 are mediated by coupling with the G protein alpha Gq/11 subunits (Schachter JB et al, 1997). P2Y2 is a potential drug target for treating cystic fibrosis (Kellerman D et al, 2002).