P2RY6:UDP P2Y6 receptor can bind to UDP Authored: Jassal, B, 2009-04-14 09:13:21 Edited: Jassal, B, 2009-04-14 09:13:21 Pubmed8670200 Pubmed9405388 Reactome Database ID Release 43417896 Reactome, http://www.reactome.org ReactomeREACT_18284 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22 The P2Y6 receptor (Communi D et al, 1996) is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. The effects of P2Y6 are mediated by coupling to stimulation of both the phosphoinositide and adenylyl cyclase pathways, a unique feature among the P2Y family (Communi D et al,1997).