Follicle-stimulating hormone receptor can bind FSH Authored: Jassal, B, 2009-02-23 11:19:01 Edited: Jassal, B, 2009-02-23 11:19:01 Follicle-stimulating hormone (FSH) is a dimeric glycoprotein hormone synthesized and secreted by gonadotropes in the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body. The actions of FSH are mediated by the FSH receptor (Minegishi T et al, 1991), found in the ovaries, testes and uterus.<br>Once activated, the receptor mediates its action by coupling to the G protein alpha-s subunit (Timossi C et al, 2002), which activates adenylate cyclase and increases intracellular cAMP levels.<br> Pubmed12039074 Pubmed1709010 Reactome Database ID Release 43391378 Reactome, http://www.reactome.org ReactomeREACT_17031 Reviewed: D'Eustachio, P, 2009-03-02 09:24:35 FSH receptor:FSH Follitropin