Neuromedin K receptor:Neurokinin B peptide Tachykinin receptor 3 (NK3) binds to neurokinin B Authored: Jassal, B, 2008-11-24 14:25:55 Edited: Jassal, B, 2008-11-26 10:37:44 Neurokinin B peptide (NKB) (Torricelli M et al, 2007) is a tachykinin-related neuropeptide that is highly expressed in the placenta.It can bind to its receptor, NK3 (Huang RR et al, 1992), which is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Elevated levels of NKB in early pregnancy may be an indicator of hypertension and pre-eclampsia (Page NM et al, 2000), and treatment with certain neurokinin receptor antagonists may be useful in alleviating the symptoms. Pubmed10866201 Pubmed1374246 Pubmed17561251 Reactome Database ID Release 43383373 Reactome, http://www.reactome.org ReactomeREACT_16953 Reviewed: D'Eustachio, P, 2009-03-02 09:24:35