Melanocortin receptors MSH MSH:Melanocortin receptors Melanocortin receptors bind melanocortins Authored: Jassal, B, 2008-12-16 10:33:44 Edited: Jassal, B, 2008-12-16 10:33:44 Melanocortins are a group of pituitary peptide hormones that include corticotropin (ACTH) and the alpha, beta and gamma melanocyte-stimulating hormones (MSH) derived from the prohormone proopiomelanocortin (Takahashi H et al, 1981). Melanocortins can act through multiple melanocortin receptors (MC1R-MC5R) (Mountjoy KG et al, 1992). The majority of melanocortin receptors (MC1R, MC3R, MC4R and MC5R) are semi-selective in their ability to bind multiple melanocortins (MSH and ACTH). MSH regulates pigmentation. Pubmed1325670 Pubmed6274691 Reactome Database ID Release 43388596 Reactome, http://www.reactome.org ReactomeREACT_16884 Reviewed: D'Eustachio, P, 2009-03-02 09:24:35