CCL27,28 CCR10:CCL27,28 Receptor CCR10 binds CCL27 and 28 ligands Authored: Jassal, B, 2008-08-21 14:07:16 CCR10 (previously known as GPR2) (Jarmin DI et al, 2000) is implicated in skin inflammation and recruits regulatory T cells to mucosal layers. CCR10 binds both CCL27 (ESkine, CTACK) (Homey B et al, 2000) and CCL28 (Mucosae-associated epithelial chemokine, MEC) (Wang W et al, 2000) and signal transduction is via increase of intracellular calcium levels. Edited: D'Eustachio, P, 2008-09-01 11:58:31 Pubmed10725696 Pubmed10725697 Pubmed10781587 Reactome Database ID Release 43373086 Reactome, http://www.reactome.org ReactomeREACT_14831 Reviewed: Bockaert, J, 2008-09-01 12:04:13