Collagen type II fibril Collagen type XI fibril Collagen type XI fibril:Collagen type II fibril Collagen XI cross-links with collagen II Authored: Jupe, S, 2012-04-30 Edited: Jupe, S, 2012-11-12 Pubmed10744725 Pubmed14602708 Pubmed17083085 Pubmed7642541 Pubmed7919525 Reactome Database ID Release 432299620 Reactome, http://www.reactome.org ReactomeREACT_150444 Reviewed: Kalamajski, Sebastian, 2012-10-08 Reviewed: Raleigh, Stewart, 2012-10-08 Reviewed: Ricard-Blum, Sylvie, 2012-11-19 Type XI collagen molecules are cross-linked by lysyl oxidase-mediated bonds (Wu & Eyre 1995) primarily in a head-to-tail manner (Eyre et al. 2006). Homopolymers of type XI collagen can form in vitro (Bruckner & van der Rest 1994, Blaschke et al. 2000). Type XI collagen molecules can cross-link with type II collagen forming heterofibrils (Eyre & Wu 2004, 2005).