Cleaved collagen type III fibril Collagen type III fibril Collagen type III degradation by MMP1,8,9,13 Authored: Jupe, S, 2011-07-12 EC Number: 3.4.21 Edited: Jupe, S, 2012-11-12 MMP1 (Welgus et al. 1981), MMP8 (Hasty et al. 1987), and MMP13 (Knauper et al. 1996, Mitchell et al. 1996), called collagenases I, II and III respectively, are all able to cleave the intrahelical bonds of collagen type III, cleaving between amino acids Gly948 and Ile949 of the Uniprot canonical sequence. MMP9 (Bigg et al. Veidal et al. 2010) and MMP10 (Stromelysin-2) are able to degrade collagen type III (Nicholson et al. 1989). Pubmed15257288 Pubmed17298441 Pubmed20666994 Pubmed2548603 Pubmed3038863 Pubmed6270089 Pubmed8576151 Pubmed8609233 Pubmed8999957 Reactome Database ID Release 431474213 Reactome, http://www.reactome.org ReactomeREACT_150222 Reviewed: Sorsa, Timo, 2012-10-08