Integrin alpha7beta1:Laminin-2 Merosin Integrin alpha7beta1 Interaction of integrin alpha7beta1 with Laminin-2 Authored: Geiger, B, Horwitz, R, 2008-05-07 08:30:32 Edited: Garapati, P V, 2008-03-11 10:20:45 Laminins are a major ECM component of basement membrane in striated muscle and are critically important for myodifferentiation. The laminin variants 2 and 4 also called as merosin, are the prevalent laminin isoforms in developing and adult muscle, and are important for muscle cell survival. Alpha7beta1 is one of the most abundant integrins in differentiated muscle fibers and the predominant laminin binding integrin present in the adult skeletal muscle. Pubmed11054877 Reactome Database ID Release 43216058 Reactome, http://www.reactome.org ReactomeREACT_13716 Reviewed: Yamada, K, Humphries, MJ, Hynes, R, 2008-05-07 08:53:37