PathwayStep7097 PathwayStep7246 PathwayStep7220 PathwayStep5411 Growth hormone receptor signaling Signaling by Interleukins Cytokine Signaling in Immune system Authored: Jupe, S, Garapati, P V, Ray, K, 2011-05-22 Cytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concentrations. Cytokines bind to specific membrane receptors, which then signal the cell via second messengers, to regulate cellular activity. Edited: Jupe, S, Garapati, P V, Ray, K, 2011-05-22 Pubmed12613569 Reactome Database ID Release 431280215 Reactome, http://www.reactome.org ReactomeREACT_75790 Reviewed: Pinteaux, E, Abdul-Sater, AA, Schindler, C, 2011-05-28 Interferon Signaling Prolactin receptor signaling