Integrin alphaVbeta5:Vitronectin Integrin alphaVbeta5 Interaction of integrin alphaVbeta5 with vitronectin Authored: Geiger, B, Horwitz, R, 2008-05-07 08:30:32 Edited: Garapati, P V, 2008-03-11 10:20:45 Pubmed9443892 Reactome Database ID Release 43216077 Reactome, http://www.reactome.org ReactomeREACT_13540 Reviewed: Yamada, K, Humphries, MJ, Hynes, R, 2008-05-07 08:53:37 The beta5 integrin subunit has been reported to only pair with the alphaV subunit. The integrin alphaVbeta5 receptor interact with vitronectin and promote cell spreading and motility on this ligand.