Collagen type VII fibril Collagen type VII dimer Formation of anchoring fibrils Authored: Jupe, S, 2012-04-30 Collagen VII forms anchoring fibrils, composed of antiparallel dimers that connect the dermis to the epidermis (Bruckner-Tuderman 2009). During fibrillogenesis, the nascent type VII procollagen molecules dimerize in an antiparallel manner. The C-propeptides are then removed by bone morphogenetic protein 1 (Rattenholl et al. 2002) and the processed antiparallel dimers laterally aggregate (Gordon & Hahn 2010). Edited: Jupe, S, 2012-11-12 Pubmed11986329 Pubmed19116634 Pubmed19693541 Reactome Database ID Release 432213195 Reactome, http://www.reactome.org ReactomeREACT_150357 Reviewed: Kalamajski, Sebastian, 2012-10-08 Reviewed: Raleigh, Stewart, 2012-10-08 Reviewed: Ricard-Blum, Sylvie, 2012-11-19