Smad7:NEDD4L Smad7:NEDD4L Translocation of Smad7:NEDD4L complex to the cytosol Authored: Orlic-Milacic, M, 2012-04-04 Co-transfection of recombinant mouse Smad7 and recombinant human NEDD4L in HepG2 cells, COS7 cells of HEK293 cells, results in the mainly cytoplasmic localization of Smad7. In the absensce of NEDD4L, Smad7 is predominantly found in the nucleus (Kuratomi et al. 2005). Edited: Jassal, B, 2012-04-10 Pubmed15496141 Reactome Database ID Release 432176428 Reactome, http://www.reactome.org ReactomeREACT_120978 Reviewed: Huang, Tao, 2012-05-14