Phosphorylation of STATs Authored: Garapati, P V, 2011-07-11 EC Number: 2.7.10 Edited: Garapati, P V, 2011-07-11 JAK2 activation results in the phosphorylation and activation of STAT1alpha, STAT3, STAT5A and STAT5B (Deberry et al. 1997, Brizzi et al. 1999, Ning et al. 2001, Ronnstrand 2004). STAT family members can be activated by JAK kinases, receptor tyrosine kinases or SFKs. LYN kinase has been identified to have role in SCF-induced phosphorylation of STAT3 (Shivakrupa & Linnekin 2005). Pubmed10358045 Pubmed15451030 Pubmed15526160 Pubmed9355737 Reactome Database ID Release 431470009 Reactome, http://www.reactome.org ReactomeREACT_111244 Reviewed: Rönnstrand, L, 2011-08-22 has a Stoichiometric coefficient of 8 p-JAK2:SFKs:p-KIT complex:STATs p-JAK2:SFKs:p-KIT complex:p-STATs