Clathrin-coated vesicle Activated TrkA receptor complex Activated TrkA receptor complex:Clathrin-coated vesicle Formation of clathrin-coated vesicle Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Both BDNF and NGF treatment recruits clathrin and AP2 (adaptor protein 2) proteins to the plasma membrane. Clathrin is the major protein of the polyhedral coat of vesicles. The AP2 complex mediates both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Edited: Jassal, B, 2006-10-10 09:20:18 Reactome Database ID Release 43177491 Reactome, http://www.reactome.org ReactomeREACT_12559 Reviewed: Greene, LA, 2007-11-08 15:39:37