Grb7 binds to the active PDGF receptor Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Grb7 an adapter protein contains a single SH2 domain, a pleckstrin homology (PH) domain, and a proline-rich region. Similar to Grb2, Grb7 interacts with phosphorylated tyrosines in pYXNX motifs, including Tyr716 and Tyr775 of the PDGF beta-receptor. Pubmed10508235 Pubmed8940081 Pubmed9739761 Reactome Database ID Release 43382055 Reactome, http://www.reactome.org ReactomeREACT_17063 Reviewed: Heldin, CH, 2008-11-23 19:29:34 PDGF:Phospho-PDGF receptor dimer:Grb7 PDGF:Phospho-PDGF receptor dimer