PI3K PDGF:Phospho-PDGF receptor dimer:PI3K PI3-kinase binds to the active receptor Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzymes which can phosphorylate phosphoinositides. These bind to and are activated by PDGF receptors. Tyr 740 and tyr 751 in PDGF beta-receptor, and tyr 731 and tyr 742 in PDGF alpha-receptor have been shown to be autophosphorylation sites and to bind PI3-kinase. <br> Pubmed1374684 Pubmed2466336 Pubmed9739761 Reactome Database ID Release 43186780 Reactome, http://www.reactome.org ReactomeREACT_17052 Reviewed: Heldin, CH, 2008-11-23 19:29:34 PDGF:Phospho-PDGF receptor dimer