NGF ligand:p75NTR:NRAGE:CHE1 NGF:p75NTR:NRAGE NRAGE sequesters CHE1 in the cytoplasm Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 CHE1, also named AATF, is an Apoptosis Antagonizing Transcription Factor in cortical neurons. NRAGE binds to CHE1, inhibiting its nuclear localization by sequestering it in the cytoplasm, and, consequently, antagonizes its anti-apoptotic function. Edited: Jassal, B, 2008-05-20 12:26:36 Reactome Database ID Release 43204958 Reactome, http://www.reactome.org ReactomeREACT_13683 Reviewed: Chao, MV, 2008-05-28 09:46:01 Reviewed: Friedman, WJ, 2008-05-20 12:23:46