eIF4E:4E-BP eIF4E:4E-BP1-P Phosphorylation of 4E-BP1 by activated mTORC1 At the beginning of this reaction, 2 molecules of 'ATP', and 1 molecule of 'eIF4E:4E-BP' are present. At the end of this reaction, 1 molecule of 'eIF4E:4E-BP1-P', and 2 molecules of 'ADP' are present.<br><br> This reaction is mediated by the 'kinase activity' of 'Activated mTORC1'.<br> Pubmed12150926 Pubmed15809305 Reactome Database ID Release 43165692 Reactome, http://www.reactome.org ReactomeREACT_6873 has a Stoichiometric coefficient of 2