Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) Authored: Jassal, B, 2008-05-19 12:57:01 GENE ONTOLOGYGO:0017144 N-acetyl-p-benzoquinone imine (NAPQI) is the reactive intermediate of the analgesic and antipyretic, acetaminophen (INN, paracetamol). At usual doses, NAPQI is quickly detoxified by conjugation but in overdose situations, NAPQI is extremely toxic to liver tissue. Pubmed10741631 Reactome Database ID Release 4376397 Reactome, http://www.reactome.org ReactomeREACT_163 Reviewed: D'Eustachio, P, 2008-05-28 08:30:54