Antizyme inhibitor binds to OAZ and stablizes ODC complex Antizyme inhibitor blocks the effects of antizyme on ODC. It has substantial similarity to ODC itself but has no ODC activity. It binds to antizyme more tightly than ODC displacing ODC from the antizyme-ODC complex. Recent studies have shown that antizyme inhibitor is able to disrupt the interaction between all forms of mammalian antizyme and ODC (Murakami et al., 1996, Nilsson et al., 2000, Mangold and Leberer, 2005). Authored: Gopinathrao, G, 2008-05-19 18:50:15 Pubmed10698696 Pubmed15355308 Pubmed15491992 Pubmed17900240 Pubmed8631929 Pubmed9349715 Pubmed9426243 Reactome Database ID Release 43350600 Reactome, http://www.reactome.org ReactomeREACT_13578 Reviewed: D'Eustachio, P, 2008-06-12 17:57:32 AZIN1 bound OAZ:ODC complex ODC:OAZ complex