Dopamine is oxidised to noradrenaline Authored: Jassal, B, 2008-10-01 13:18:42 Dopamine beta-hydroxylase (DBH; dopamine beta-monooxygenase) is a copper-containing glycoprotein consisting of four identical subunits and catalyzes the oxidation of dopamine to norepinephrine. It requires ascorbic acid as an electron donor. DBH is localized in the norepinephrinergic and epinephrinergic neurons in the central nervous system. The enzyme exists in the secretory vesicles as both soluble and membrane-bound forms. The soluble form is secreted with catecholamines by exocytosis whereas the membrane-bound form is recycled into the vesicles. EC Number: 1.14.17.1 Edited: Jassal, B, 2008-01-08 13:51:41 Pubmed1857555 Pubmed3443096 Pubmed7961964 Reactome Database ID Release 43209891 Reactome, http://www.reactome.org ReactomeREACT_15372 Reviewed: D'Eustachio, P, 2008-05-28 08:30:54