Iodide is taken up by thyroid epithelial cells Authored: Jassal, B, 2008-10-01 13:18:42 Edited: Jassal, B, 2008-01-08 13:51:41 Iodide (I-) is transported from blood serum into the thyroid cell by the Na+/I- symporter (sodium/iodide). This intrinsic membrane protein uses energy from the inward movement of Na+ to drive the process and accumulate I- in the cell, maintaining a cellular concentration 30-40 times that of the serum concentration. This process, also called the iodide trap, is stimulated by TSH (thyroid stimulating hormone) and is saturable by large amounts of I-. Pubmed8806637 Reactome Database ID Release 43209910 Reactome, http://www.reactome.org ReactomeREACT_15327 Reviewed: D'Eustachio, P, 2008-05-28 08:30:54 has a Stoichiometric coefficient of 2