Synthesis of glyoxylate from hydroxyproline Authored: D'Eustachio, P, 2009-01-11 19:48:01 Biochemical studies of rat and bovine liver extracts suggest that conversion of hydroxyproline to glyoxylate takes place in the mitochondria in four steps. The human enzymes that catalyze these reactions have not been identified (Adams and Frank 1980; Adams and Goldstone 1960; Valle et al. 1979; Scholtz and Schuster 1986). In addition, transport processes must exist to enable initially cytosolic hydroxyproline to enter the mitochondria, and to enable the mitochondrial glyoxylate to move to peroxisomes. Edited: D'Eustachio, P, 2009-03-03 14:28:53 Pubmed13681370 Pubmed3942759 Pubmed500817 Pubmed6250440 Reactome Database ID Release 43389859 Reactome, http://www.reactome.org ReactomeREACT_16896 Reviewed: Jassal, B, 2009-03-03 14:29:24