<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/HINO?iri=http://purl.obolibrary.org/obo/HINO_0024387"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002233 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002233"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002234 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002234"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/HINO_0011947 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0011947">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GRB2:SOS1</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0023540 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0023540">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GRB2:SOS1:P-ERBB2:P-EGFR</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0024387 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0024387">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GRB2:SOS1 complex binds phosphorylated EGFR:ERBB2 heterodimer</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/INO_0000040"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0011947"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0027172"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002234"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HINO_0023540"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Authored: Orlic-Milacic, M, 2011-11-04</rdfs:comment>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Edited: Matthews, L, 2011-11-07</rdfs:comment>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phosphorylated ERBB2:EGFR heterodimer recruits GRB2:SOS1 complex through phosphorylated tyrosine residues on either ERBB2 or EGFR that serve as direct docking sites for GRB2.</rdfs:comment>
        <ns3:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pubmed8530511</ns3:IAO_0000119>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome Database ID Release 431250488</rdfs:seeAlso>
        <ns3:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reactome, http://www.reactome.org</ns3:IAO_0000119>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ReactomeREACT_116115</rdfs:seeAlso>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reviewed: Neckers, LM, 2011-11-11</rdfs:comment>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reviewed: Xu, W, 2011-11-11</rdfs:comment>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HINO_0027172 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HINO_0027172">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Phosphorylated ERBB2:EGFR heterodimers</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/INO_0000040 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/INO_0000040"/>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



