NRGs/EGFLs:ERBB4 ERBB4:ERBB3 heterodimer NRG1/2:ERBB3 ERBB4 forms heterodimers with ERBB3 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Edited: Matthews, L, 2011-11-07 Ligand-stimulated ERBB4 was shown to form heterodimers with ligand-stimulated ERBB3 when human ERBB4 and ERBB3 were exogenously expressed in mouse pro-B-lymphocyte cell line. Heterodimers of ERBB4 and ERBB3 undergo trans-autophosphorylation, but the exact phosphorylation pattern, downstream signaling and physiological significance of these heterodimers have not been studied. Pubmed7565730 Reactome Database ID Release 431977958 Reactome, http://www.reactome.org ReactomeREACT_115947 Reviewed: Harris, RC, 2011-11-11 Reviewed: Zeng, F, 2011-11-11