arginine + H2O => ornithine + urea [ARG1] Authored: D'Eustachio, P, 2003-06-24 00:00:00 Cytosolic Arginase 1 (ARG1) trimer catalyzes the hydrolysis of arginine to yield ornithine and urea (DiCostanzo et al. 2005). Patients expressing mutated forms of the enzyme with diminished in vitro arginase activity can accumulate arginine to pathogenic levels in the blood (e.g., Uchino et al. 1995). EC Number: 3.5.3.1 Edited: D'Eustachio, P, 2003-06-24 00:00:00 Pubmed16141327 Pubmed7649538 Reactome Database ID Release 4370569 Reactome, http://www.reactome.org ReactomeREACT_394